abbelight SAFe180是一款基于單分子定位技術的顯微成像（SMLM）的超分辨模塊。該設備具有高度靈活性，能夠搭載在絕大多數的倒置顯微鏡上，并且僅僅需要使用一個C-mount（CCD或CMOS所連接的部位）接口，即可將您的倒置顯微鏡直接升級為超分辨成像系統。并且改造過程不會破壞原有顯微鏡系統的光路和功能，不會與其它的顯微鏡改造相沖突。

    本設備既在配置上的選擇也十分靈活。它既可以作為顯微鏡的一個升級配件來改造您的顯微鏡，也擁有完整的超分辨系統。讓用戶在獲得專業的圖像質量的同時，享受到經濟合理的超分辨升級方案。

設備參數

+  模塊化系統：可接到大多數倒置熒光顯微鏡

+  成像模式：PALM、STORM、smFRET、PAINT、SPT

+  光源模式：Epi、TIRF、HILO

+  超高分辨率：25 nm的XY軸分辨率，50nm的Z軸分辨率

+  超大視野：180 × 180 μm2的視野

+  全自動化控制

+  無需高功率激光光源

配套試劑

測試數據

發表文章

[1] Cabriel, Clément, et al. "Combining 3D single molecule localization strategies for reproducible bioimaging." Nature communications 10.1 (2019): 1980.

[2] Woodhams, Stephen G., et al. "Cell type–specific super-resolution imaging reveals an increase in calcium-permeable AMPA receptors at spinal peptidergic terminals as an anatomical correlate of inflammatory pain." Pain 160.11 (2019): 2641-2650.

[3] Belkahla, Hanen, et al. "Carbon dots, a powerful non-toxic support for bioimaging by fluorescence nanoscopy and eradication of bacteria by photothermia." Nanoscale Advances (2019).

[4] Denis, Kevin, et al. "Targeting Type IV pili as an antivirulence strategy against invasive meningococcal disease." Nature microbiology 4.6 (2019): 972.

[5] Szabo, Quentin, et al. "TADs are 3D structural units of higher-order chromosome organization in Drosophila." Science advances 4.2 (2018): eaar8082. 

[6] Boudjemaa, Rym, et al. "Impact of bacterial membrane fatty acid composition on the failure of daptomycin to kill Staphylococcus aureus." Antimicrobial agents and chemotherapy 62.7 (2018): e00023-18.

[7] Culley, Sian, et al. "Quantitative mapping and minimization of super-resolution optical imaging artifacts." Nature methods 15.4 (2018): 263.

[8] Berger, Stephen L., et al. "Localized myosin II activity regulates assembly and plasticity of the axon initial segment." Neuron 97.3 (2018): 555-570.

[9] Cabriel, Clément, et al. "Aberration-accounting calibration for 3D single-molecule localization microscopy." Optics letters 43.2 (2018): 174-177. 

[10] Bouissou, Ana?s, et al. "Podosome force generation machinery: a local balance between protrusion at the core and traction at the ring." ACS nano 11.4 (2017): 4028-4040. 

[11] Sellés, Julien, et al. "Nuclear pore complex plasticity during developmental process as revealed by super-resolution microscopy." Scientific reports 7.1 (2017): 14732.

[12] Bourg, Nicolas, et al. "Direct optical nanoscopy with axially localized detection." Nature Photonics 9.9 (2015): 587. 

用戶單位